The demand for RRT among patients with COVID-19 has increased fivefold in comparison to the historical US populations (4.9% as of 2020 VS. 0.9% earlier) (Source: American Society of Nephrology, 2021). According to an article published by the International Society of Nephrology 2020, countries such as China and Italy reported AKI rates as high as 29%. The early initiation of continuous renal replacement therapy (CRRT) is an important step to curbing the rising incidence of AKI due to the COVID-19 infection.  

The growing worldwide incidence of AKI/AKF is, therefore, expected to increase the demand for CRRT. According to the International Society of Nephrology (INR), an estimated 13.3 million cases of AKI are registered annually worldwide.  

The increasing incidence of acute renal disease, the availability of advanced CRRT disposables and replacement fluids, and increasing government initiatives to increase awareness about CRRT are expected to drive market growth in the coming years. 

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The high growth rate of the CVVHDF segment can be attributed to its flexibility as compared to other CRRT modalities. The CVVHDF modality also combines the benefits of convection and diffusion for the removal of solutes, which is another major factor supporting its growth. 


The analysis of market developments between 2018 and 2021 revealed that several growth strategies such as research collaborations and partnerships were adopted by market players to strengthen their product portfolios and maintain a competitive position in the Continuous Renal Replacement Therapy Market

CRRT is a highly specialized and critical therapy that involves complex nursing care. Properly trained ICU nurses are required for the continuous assessment of indications, ensuring good vascular access, avoiding unnecessary interruptions, and preventing complications in patients during CRRT. However, currently, there is a dearth of registered nurses in ICU settings. Moreover the complexity associated with CRRT are likely to hinder the market growth.